Fakultäten » Medizinische Fakultät » Hirnforschung, Institut für » Prof. Dr. Martin E. Schwab » Schwab
| Title / Titel | Functional aspects of spinal cord and brain lesions, regeneration and plasticity | ||||||
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| Abstract (PDF, 14 KB) | |||||||
| Summary / Zusammenfassung | After a lesion of the CNS such as stroke or spinal cord injury only few injured nerve fibres spontaneously regenerate. This growth inhibition is partly due to the presence of myelin-associated growth inhibiting proteins that can be neutralized e.g. by specific antibodies. Using this approach functional recovery after specific CNS lesions is studied in rodent models. Next to classical behavioral analysis after injury and anatomical reconstructions novel imaging techniques are applied to study plastic effects both in the spinal cord and in the cortex. In addition, we are investigating the role of training and motivation for regeneration and plasticity. Weitere Informationen |
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| Publications / Publikationen | Weitere Informationen | ||||||
| Keywords / Suchbegriffe | regeneration, plasticity, spinal cord injury, stroke, Nogo-A antibodies | ||||||
| Project leadership and contacts / Projektleitung und Kontakte |
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| Funding source(s) / Unterstützt durch |
Forschungskredit der Universität Zürich, SNF (Personen- und Projektförderung), SNF (Programm NFS/NCCR), EU, Foundation, Private Sector (e.g. Industry) private donations |
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| In collaboration with / In Zusammenarbeit mit |
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| Duration of Project / Projektdauer | Jan 2007 to Jul 2014 |